Shiri's Substances Expanded

Pharmaceuticals are one of the most profitable kinds of products on Earth. As it turns out, the corporation has been producing a lot more than we thought.

This mod adds a huge variety of new substances to the game, from the disorienting pain relief of ketamine to the full visual assault of dimethyltryptamine.

Made with real pharmacology data to be as medically accurate as possible without sacrificing fun, as well as creating as much depth as possible from simple foundations. Substances have not only primary, but secondary, and even tertiary effects, as well as interactions and knock-ons.

Disclaimer: DMT causes extreme flashing lights. Do not use if you suffer from photosensitive epilepsy. This mod does not glorify substance use; reckless administration results in overdose and potential death, and repeated use leads to addiction.

Sedatives

Four classes of sedatives, each with their own drawbacks.

Diphenhydramine

A sedative antihistamine. Safe and hard to overdose on, but not as effective as other methods.

An older partial alpha-2 adrenergic agonist. Safe and highly effective, but causes hypotension.

The classic benzodiazepine. Safe, effective, and easy to dose, but extremely addictive with horrific withdrawals.

Phenobarbital

The classic barbiturate. Highly effective and not very addictive, but extremely dangerous to overdose on, with a very small margin of error.

Pain Relief

One dissociative anaesthetic.

Provides entirely unmatched pain relief, but causes effects mimicking brain damage for its duration.

Performance Enhancement

One anabolic steroid.

Testosterone

Increases your strength over time, but holds a potential for abuse.

Nutrition Management

One appetite suppressant and one thirst suppressant (the only fictional drug in the roster) along with a diuretic.

Semaglutide

Pauses your hunger.

Vigatrodipsin

Pauses your thirst, but drains fluid if above 60.

Hydrochlorothiazide

Rapidly drains fluid from your body.

Mood Management

Three psychedelics.

A mild psychedelic. Lifts your mood slightly and causes effects mimicking brain damage for its duration.

LSD (Lysergic Acid Diethylamide)

A moderate psychedelic. Lifts your mood and causes effects mimicking brain damage for its duration.

DMT (Dimethyltryptamine)

An exceptionally strong psychedelic. Greatly lifts your mood but causes an extreme effect for a short time. If you suffer from photosensitive epilepsy, do not use this drug, as it creates an extremely intense flashing effect.

Recreation

A stimulant, two cannabinoids, and an entactogen.

The classic stimulant. Lifts mood, pauses hunger, and increases energy. Can be smoked or used through patches/gum. Three times as addictive as heroin, it becomes less effective over time and causes severe withdrawals. Also impacts lung function if smoked, with the filter type determining how intensely lung function is impacted.

Contains both CBD and THC at levels depending on which strain of 4 is rolled. Can be smoked or ingested via edibles.

CBD (Cannabidiol)

A non-psychoactive cannabinoid. Reduces pain and anxiety.

THC (Tetrahydrocannabinol)

A psychoactive cannabinoid. Improves mood temporarily and makes you hungrier.

MDMA (Methylenedioxymethamphetamine)

An entactogen. Boosts energy and mood, as well as making you more sociable and charismatic. Causes mood loss when the high is over.

Crafting

Several substances can be synthesised from raw materials found in the world. Chemistry gear, precursor items, and reagents spawn throughout the layers and can be combined to produce drugs in multiple batches, making synthesis more resource-efficient than relying on loot alone.

Precursors are hidden in plain sight. Nail polish, perfume, road markers, and other everyday cargo contain the chemical building blocks for substances in the roster. Some recipes require the full chemistry kit, while others only need a few components.

Cannabis and tobacco can be broken down and recombined into new products. Joints, spliffs, blunts, and cigarettes can all be crafted from raw materials, and cannabis can be infused into food using a heat source to produce edibles.

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